Inerestingly I landed on this thread, so I went ahead and turned acpi=off in grub, and also blacklisted the i2c_piix4 in my brand new Epyc-based server, which had one error so far. I was running a heavily loaded postgres database on a linuxraid raid 0 striped, across my 2 NVMEs. I have now split the NVMEs, i.e. dropped the raid, and reloaded the database onto a single NVME. I doubt it would make much difference with the throughput there.

here is my error, which I have still not seen again after the blacklists: