That's an odd one. I've just done a search round the net for you and here's some of the possible solutions i've found:
1) You may want to run /sbin/mouseconfig from a root console within kde and see which magical combination brings it to life after it freezes
2) But from what I've read it sounds like more of a USB controller type problem and the solution may be found in the XF86Config file, a user who had a healthy MIcrosoft Optical Mouse in Suse had a config file like this:
Option "Device" "/dev/usbmouse"
Option "Name" "Autodetection"
Option "Protocol" "imps/2"
Option "Vendor" "Sysp"
Option "ZAxisMapping" "4 5"
I've just had a quick look on Linux Compatible
and I can't find a problem either. So I'm guessing that its probably something to do with XF86, I'd try asking here
they might be able to help you better.
Hope that helps.