I have a HP DL380G4 with a XEON 3G EM64T processor and wonder why mysql only supports Fedora 2 and not 3 when it´s about EM64T. Is there support for EM64T in FC2 or only in from FC3 and up?
Running 32bit fedora everything from fedora1 onwards will treat the processor like a Xeon and get good performance.
In terms of 64bit to get the specific kernel extensions for EM64T you'll probably need Fedora3 or above. However if you really wanted to you could install an older version of Fedora and custom compile a newer kernel.
To be honest the version of fedora you use isn't going to make that much difference they will all work just fine as mysql servers.