Welcome to fedora, Fedora 15 with the DE of your choice.
Gnome is the "standard", alternates are released as spins
Most hardware drives come from the kernel, so support is about the same across all distros.
Third party drivers, nvidia / ati / some wireless drivers come from third parties, so in those cases sometimes people can guide you , but ultimately support comes from the third parties as the drivers are now written by Fedora and are closed source. Again support for third party drivers is about the same on all distros.