Good work, scottro. That was just the resource I needed.
By default F10 creates a virbr0 which is configured to DHCP to guests and NAT to the physical network. This allows outbound, but firewalls inbound. The trick is to slave a physical NIC to a bridge that will enable routing.
Adding the following script to /etc/sysconfig/network-scripts/ as ifcfg-nvet1 does just that:
#!/bin/sh
IF="eth1"
NET="192.168.0"
HOST="100"
BR="virbr1"
brctl addbr $BR
ifconfig $IF 0.0.0.0
brctl addif $BR $IF
ifconfig $BR $NET.$HOST netmask 255.255.255.0 up
route add -net $NET.0 netmask 255.255.255.0 $BR
route add default gw $NET.1 $BR
exit 0
By using this directory and name for the file, it enables the bridge at boot time. This would allow VMs on the host to use addresses on the specified subnet. Since the interface is slaved to the bridge, an ifconfig shows no IP for eth1, but instead for virbr1.
The assumption is that this card is the system's primary interface.