Here's the best method that I've had for my Windows friends. I personally run this in Safe Mode to avoid having the viruses load any more than absolutely necessary at start-up.
The top three links are to the tools and the instructions follow:
Sysclean:
http://www.trendmicro.com/download/dcs.asp
LPT Virus Pattern files:
http://www.trendmicro.com/download/viruspattern.asp
Spyware Pattern files:
http://www.trendmicro.com/download/spywarepattern.asp
I. Description
This self-extracting archive is a stand-alone fix package that
incorporates the Trend Micro VSAPI Malware and Spyware scanning engines
as well as the Trend Micro Damage Cleanup Engine and Template.
This tool supports the following features:
o Terminate all detected malware/spyware instances in memory
o Remove malware/spyware registry entries
o Remove malware/spyware entries from system files
o Scan for and delete all detected malware/spyware copies in all local
drives
II. File List
o sysclean.com - the main executable module
o readme.txt - this file
o lpt$vpn.XXX - malware pattern file (see Requirements)
o ssapiptn.da5 - spyware pattern file (see Requirements)
III. Requirements
1. Download the latest versions of the following pattern files:
lpt$vpn.XXX in ZIP format as lptXXX.ZIP
from the following location:
<http://www.trendmicro.com/download/viruspattern.asp>
ssapiptn.da5 in ZIP format as ssapiptnXXX.ZIP
from the following location:
<http://www.trendmicro.com/download/spywarepattern.asp>
These files must be saved in the same folder where you run
this fix package.
2. This tool is designed to run under Windows NT/2000/XP/2003/VISTA 32-bit.
For users running Windows NT 4.0, you need to copy the file, PSAPI.DLL,
to the Windows system directory, which is usually C:\WINNT\system32.
You can find the file in the Windows NT 4.0 Setup CD at the
following locations:
\Support\Debug\i386\PSAPI.DLL
3. The Trend Micro Spyware Engine only supports Windows 2000/XP/2003/VISTA 32-bit
systems. The spyware scan feature is disabled in lower versions of
the Microsoft operating systems.
IV. How to Use
Performing System Scan and Cleanup
1. Create a temporary folder and copy SYSCLEAN.COM into this folder.
NOTE: This temporary folder should be created on a local or mapped drive.
2. Download latest malware and spyware pattern files.
Extract the downloaded ZIP pattern files into the created folder.
3. Close all applications running on your system, including any
antivirus software.
4. Run the executable file, SYSCLEAN.COM, by either:
a. Double-clicking the tool in Windows Explorer.
b. Executing it via command prompt using syntax based on the
aforementioned parameters.
5. Enable any antivirus software that is installed on your system and
perform a manual scan.
NOTE: This fix tool generates the log file, SYSCLEAN.LOG, in its
current folder.
Good luck with it.